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KMID : 0358320070480010029
Korean Journal of Urology
2007 Volume.48 No. 1 p.29 ~ p.34
Comparative Analysis of Clinical Parameters in Acute Pyelonephritis
Jung Yon-Hwan

Cho In-Rae
Lee Seung-Eon
Lee Keon-Cheol
Kim Jong-Gu
Jeon Joon-Seong
Park Seok-San
Roh An-Sik
Yang Won-Jae
Sung Luck-Hee
Chung Jae-Yong
Noh Choong-Hee
Chung Jae-Il
Min Kweon-Sik
Kang Dong-Il
Choi Sung-Hyup
Kim Duk-Yoon
Lee Sang-Don
Kim Hong-Sup
Lee Dong-Hyun
Seong Do-Hwan
Chang Young-Seop
Song Ki-Hak
Lee Kyung-Seop
Park Dong-Soo
Kim Young-Ho
Kim Min-Eui
Abstract
Purpose: To compare the variable inflammatory parameters of acute pyelonephritis patients treated with inpatient therapy at 13 hospitals, according to the age and gender distributions.

Materials & Methods: A total of 3,544 medical records of patients with confirmed acute pyelonephritis, and admitted to hospital between January 2000 and December 2005, were retrospectively analyzed.

Results: The mean age of the patients was 43.2¡¾16.2 years old, with a male:female ratio of 1 : 5.1. The average duration of hospital admission was 7.9¡¾5.3 days. Underlying diseases were found in 23.0%(749/3,252 patient), largely due to diabetes(35.1%). Radiological abnormal findings were found in 13.7%. The leukocyte count, ratio of segmented form, erythrocyte sedimentation rate(ESR), c-reactive protein, pyuria, positive blood culture, positive urine culture were 11,014¡¾5,778/mm3, 74.8¡¾14.5%, 44.0¡¾32.0 mm/hr, 12.4¡¾9.3mg/dl, 83.9%, 10.5% and 46.7%, respectively. E. coli grow in 79% of the urine culture positive patients. In a comparison of 3 age groups (£¼40 years, 40-60 years, £¾61 years), the elderly patients had a greater number of underlying diseases and more pathogens in cultured blood. When divided into males and females, the elderly male patients had more pathogen in cultured urine, but contrary to the male patients, the elderly female patients had elevated leukocyte count and erythrocyte sedimentation rate. Also, the old patient group had more resistance to ampicillin when they had E. coli as the uropathogen(p=0.021). Patients with higher ESR required longer hospital admission periods.

Conclusion: It was found that variable clinical parameters of acute pyelonephritis patients treated with inpatient therapy differed according to both gender and age group in Korea. Therefore, these factors should be taken into account in the treatment plan.(Korean J Urol 2007;48:29-34)
KEYWORD
Acute pyelonephritis, Inpatients
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