KMID : 0358320070480010029
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Korean Journal of Urology 2007 Volume.48 No. 1 p.29 ~ p.34
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Comparative Analysis of Clinical Parameters in Acute Pyelonephritis
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Jung Yon-Hwan
Cho In-Rae Lee Seung-Eon Lee Keon-Cheol Kim Jong-Gu Jeon Joon-Seong Park Seok-San Roh An-Sik Yang Won-Jae Sung Luck-Hee Chung Jae-Yong Noh Choong-Hee Chung Jae-Il Min Kweon-Sik Kang Dong-Il Choi Sung-Hyup Kim Duk-Yoon Lee Sang-Don Kim Hong-Sup Lee Dong-Hyun Seong Do-Hwan Chang Young-Seop Song Ki-Hak Lee Kyung-Seop Park Dong-Soo Kim Young-Ho Kim Min-Eui
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Abstract
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Purpose: To compare the variable inflammatory parameters of acute pyelonephritis patients treated with inpatient therapy at 13 hospitals, according to the age and gender distributions.
Materials & Methods: A total of 3,544 medical records of patients with confirmed acute pyelonephritis, and admitted to hospital between January 2000 and December 2005, were retrospectively analyzed.
Results: The mean age of the patients was 43.2¡¾16.2 years old, with a male:female ratio of 1 : 5.1. The average duration of hospital admission was 7.9¡¾5.3 days. Underlying diseases were found in 23.0%(749/3,252 patient), largely due to diabetes(35.1%). Radiological abnormal findings were found in 13.7%. The leukocyte count, ratio of segmented form, erythrocyte sedimentation rate(ESR), c-reactive protein, pyuria, positive blood culture, positive urine culture were 11,014¡¾5,778/mm3, 74.8¡¾14.5%, 44.0¡¾32.0 mm/hr, 12.4¡¾9.3mg/dl, 83.9%, 10.5% and 46.7%, respectively. E. coli grow in 79% of the urine culture positive patients. In a comparison of 3 age groups (£¼40 years, 40-60 years, £¾61 years), the elderly patients had a greater number of underlying diseases and more pathogens in cultured blood. When divided into males and females, the elderly male patients had more pathogen in cultured urine, but contrary to the male patients, the elderly female patients had elevated leukocyte count and erythrocyte sedimentation rate. Also, the old patient group had more resistance to ampicillin when they had E. coli as the uropathogen(p=0.021). Patients with higher ESR required longer hospital admission periods.
Conclusion: It was found that variable clinical parameters of acute pyelonephritis patients treated with inpatient therapy differed according to both gender and age group in Korea. Therefore, these factors should be taken into account in the treatment plan.(Korean J Urol 2007;48:29-34)
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KEYWORD
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Acute pyelonephritis, Inpatients
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